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6-bromoandrostenedione
Chemical Name: 6-Bromo androstane-3,17-dione
CAS#:38632-00-7
Assay: 97%
A selective inhibitor of aromatase (estrogen synthetase) would be a useful pharmacological
tool with potential therapeutic application. We have found that 6 alpha-bromoandrostenedione
(6 alpha-BrA) is a competitive inhibitor of human placental aromatase with respect to
androstenedione, with an apparent Ki of 3.4 nM, while 6 beta-BrA is a mechanism-based
irreversible inhibitor with an apparent Ki of 0.8 microM and a kinact of 0.025 min-1.
Aromatase activity was measured by tritium release into water from the 1 beta position of
[1(-3)H,4(-14)C]androstenedione in reaction mixtures containing NADPH and the aromatase.
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| Posted by |
Steven Yu
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| e-Mail | Contact company |
Company
| Wuhan Yuancheng Technology Development Co.
| | Address | MSN: ychp5488@hotmail.com, Zhongshan Road | City & ZIP
| Wuhan
| Country
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| Phone
| For registered Members only.
| Fax
| For registered Members only.
| | Interest | | | Company Profile | As one of largest manufacturers of chemical raw materials and cinnamate series in China, our main products include Cinnamic Acid, Cinnamic Aldehyde, Cinnamic Alcohol, Methyl Cinnamate,Ethyl Cinnamate, Cinnamonitrile, Cinnamyl Acetate, Cinnamyl Chloride, P-Hydroxycinnamic Acid, 6-Bromoandrostenedione,Octyl methoxycinnamate, 3-trifluoromethylcinnamaldehyde, Cinnamamide, 4-Bromostyrene, P-Methoxycinnamic acid, Testosterone series, Trenbolone series, Nandrolone series, Methenolone series, Melatonin, L-carnitine, D-Biotin pure,Vitamin B1, Vitamin E oil 96%, steroid hormone and so on.Our products have passed ISO 9001, and we have got KOSHER certificates. We also distribute pharmaceutical raw materials from our affiliated factories like Aspartame, Sucralose, Metronidazole, Arbutin, Paclitaxel, Zeaxanthin, CozymeQ10 and many kinds of vitamins. We hope to find more friends through the internet, and welcome contact me freely via SKYPE: steven.y6. | | URL | For registered Members only. | | Rating |  (0 reviews) | | Popular tags | | |
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 | | Keywords (seperate by comma) | 6-bromoandrostenedione, 38632-00-7 | | Product Specifications | 6-bromoandrostenedione
Chemical Name: 6-Bromo androstane-3,17-dione
CAS#:38632-00-7
Assay: 97%
A selective inhibitor of aromatase (estrogen synthetase) would be a useful pharmacological tool with potential therapeutic application. We have found that 6 alpha-bromoandrostenedione (6 alpha-BrA) is a competitive inhibitor of human placental aromatase with respect to androstenedione, with an apparent Ki of 3.4 nM, while 6 beta-BrA is a mechanism-based irreversible inhibitor with an apparent Ki of 0.8 microM and a kinact of 0.025 min-1. Aromatase activity was measured by tritium release into water from the 1 beta position of [1(-3)H,4(-14)C]androstenedione in reaction mixtures containing NADPH and the aromatase.
| | Industry Category | chemical | | Quality/Safety Certifications | ISO9001 | | Delivery Lead Time | 365days | | Payment & Price Terms | T/T | | My Offers | Beta-Bromostyrol 103-64-0 98%
4-Bromostyrene 2039-82-9 98%
2-Bromostyrene 2039-88-5 98%
Allyl phenoxyacetate 7493-74-5
Sodium cinnamate 538-42-1 98%
Potassium cinnamate 16089-48-8 99%
P-methoxycinnamic chloride 98%
3-(trifluoromethyl)cinnamoyl chloride None 98%
3-(trifluoromethyl)cinnamyl chloride None 97%
3-(trifluoromethyl)cinnamic alcohol None 98%
1,3-Dimethoxybenzene None 98%
3,3-diphenylpropenyl chloride 98%
Alpha-(trichloromethyl)benzyl acetate 90-17-5 98%
Ferulic acid 1135-24-6 99%
Caffeic acid 331-39-5 99%
Cinnamamide 621-79-4 98%
Cinnamoyl chloride 102-92-1 98%
Cinnamyl Chloride 2687-12-9 97%
6-Bromo androstane-3,17-dione 38632-00-7 97%
4-Fluorocinnamoyl chloride 13565-08-7 98%
| | Other Products | | | Customers | Givaudan,Symrise,Ventos | | Detailed Company Introduction | | | FOB Price & Port | 5000000 | | Packaging Details | 230 | | Person in Charge | 230 | | Web Site | For registered Members only. |
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| Product Details |
| Product id |
220537 |
| Visits |
176 |
| Date |
2008.12.01 |
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