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Main usage: It is used in women who have experienced menopause (change of life; end of monthly menstrual periods) to:
treat breast cancer that has spread within the breast or to other areas of the body.
treat early breast cancer in women who have already been treated with surgery, radiation and/or chemotherapy. Letrozole is sometimes used right after these treatments and sometimes after 5 years of treatment with a medication called tamoxifen (Nolvadex). Letrozole is used to stop any cancer cells that remain after these treatments from spreading.