Function:

Semi-synthetic broad-spectrum antibiotics; Low toxicity; antivirus; cure and prevention the disease like meningitis, endocarditic; respiratory infection; endocrine infection.

Introduction:

Ampicillin is a beta-lactam antibiotics that has been used extensively to treatbacterial infections since 1961. It is considered part ofthe penicilin family and is roughly equivalent to amoxicilin in terms of spectrum and level of activity . It can sometimes result in non-allergic reactions that range in severity from a rash.

Belonging to the Penicillin group of beta-lactam antibiotics, ampicillin is able to penetrate Gram-negative and some Gram-negative bacteria. It differs from penicillin only by the presence of an amino group. That amino group helps the drug penetrate the outer membrane of gram-negative bacteria.

Ampicillin acts as a competitive inhibitor of the enzyme transpeptidase, which is needed by bacteria to make their cell walls.It inhibits the third and final stage of bacterial cell wall synthesis in binary fission, which ultimately leads to cell lysis